Frequently Asked Questions


Who are we?

As a premier clinical research organization, we have conducted more than 1,000 clinical trials over 20 years and have worldwide recognition for providing patients access to cutting edge medical research. If you have a medical issue and want a research solution, or if you are a healthy volunteer, come visit our center and learn more. One of our experts will be happy to evaluate you.



What are Clinical Trials?

Clinical trials are controlled research studies that monitor the safety and effectiveness of medications or devices for human use. Clinical trials involve many different aspects of research. Some trials test new, cutting edge medications, while others test new combinations or applications of medications that have not been previously approved. All trials, however, require the participation of volunteers in order to advance medicine as a whole. The volunteers are medical heroes!



How do Patients Benefit from Participating in Clinical Trials?

There are numerous benefits from participating in a clinical trial. Many of our volunteers appreciate the access to cutting edge treatments. Others participate to receive potentially expensive study medications and treatments at no cost, as well as compensation for their time and travel. Lastly, our patients love the sense of community and civic service they feel knowing that their participation contributed to advancement of medicine. The Center for Information & Study on Clinical Research Participation (CISCRP) found that 95% of participants who completed a clinical trial were interested in participating in another!



Are Clinical Trials Safe?

Many people who have not previously participated in a clinical trial are concerned about the safety of participating. The safety of our volunteers is our number one concern! Unline most situations in life, while participating in a clinical trial you have constant access to medical care and qualified staff who monitor your wellbeing with meticulous attention to detail. Our doctors, nurses, and study coordinators will support you throughout the clinical trial process.

All pharmaceutical research goes through an extensive preclinical testing process before it ever reaches human patients to make sure it is as safe and effective as possible. Every clinical trial in the US must pass rigorous regulations and be monitored by an Institutional Review Board (IRB) to ensure the risks of the trial are as minimal as possible and worthy of any possible benefits to the participant.



The Guinea Pig Myth

A common misconception about clinical trials is that participants are research "guinea pigs." This statement could not be further from the truth. Historically guinea pigs were used in research because of similarities they share with humans. However, guinea pigs do not have the ability to understand what a clinical trial involves and sign an informed consent. An informed consent form is a document that describes the goal of the study, what risk is involved, the possible benefits to the patient, and potential patient compensation. As mentioned above, all clinical trials are monitored by IRBs that ensure the tirals are ethical and as safe as possible for human participation. Research volunteers are not guinea pigs. However, participants are just as important to future medical breakthroughs as guinea pigs were to the discoveries of vitamin C and the tuberculosis vaccine!



The Phases of a Clinical Trial

Clinical trials are divided into different states called phases. The earlies phase trials look at whether a drug is safe or the side effects it causes. Later phase trials aim to test whether the new treatment is better than existing treatments.

  • Phase I involves the testing of IP's (investigational products) for safety in humans for the first time. Phase I trials typically involve a small number of either healthy volunteers or people with the disease/condition.
  • Phase II trials continue to monitor the safety of the IP and determine its effective dose. These trials involve several hundred volunteers.
  • Phase III trials measure the effectiveness of the IP to treat a designated condition. These trials are large scale and involve hundreds to thousands of volunteers.
  • Phase IV trials are often required by the FDA and are designed to measure long term safety and efficacy of IP's after they are approved.


Who pays for this research?

Sponsors such as pharmaceutical companies, governments and foundations fund medical research through study grants. The grant provides the funding to conduct the study at local research sites, so you don't pay a thing. In fact, we don't even ask for your insurance information.



How long do the programs last?

Depending on the type of research, studies can last from a few weeks to several years. Each program is designed to collect specific information, but volunteers will know before enrollment how long the study is expected to last and exactly how many visits to the research site will be required.



How do I know if I am qualified?

Because each research program is unique and has specific enrollment criteria, the best way to find out if you qualify for a clinical research study is to either call us or come in for a free evaluation. Whether you have a medical issue and want to explore research solutions, or you are a healthy volunteer, come visit one of our research sites and find out more. There is never an obligation, and one of our experts will be happy serve you.



Pfizer - Before it Became a Medicine


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Watch what they have to say about their research experience!



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Phase 1 Research Joe's Experience
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Our Specialists


Nina Smith

Nina is probably one of the most active members of our Clinical Research family. On the weekends, she volunteers as a co- leader for a Girl Scout troop, enjoys going to her two daughters’, Abigail (10) and Gianna (5), soft ball games, and eats dinner with her parents and brother’s family on Sunday nights. When she is not selling thin mints, in charge of camping trips, or leading girl scout trips to theme parks, she enjoys wine tasting, collecting antiques, and rooting for the Gators. “I graduated from the University of Florida, therefore I will always be a gator fan, winning or losing, although I don’t know a lot about sports” she admits. 

During the week, she manages the office at Nature Coast Clinical Research, Crystal River location. Nina has been a member of our research family for 5 years and continues to be a valuable asset to the company. She has been working in the medical field since high school. Even when not at work, Nina enjoys being entertained by medicine and patient care. "I love to watch medical shows of any kind, anything from Grey’s Anatomy to Monsters Inside Me. I like to point out errors on the fictional medical shows."

Lisa Meyers

To look at her, you would probably not guess that Lisa Meyers and her husband have six active children ranging in age from 8 months to 13 years. You probably would presume that she is very busy and you would be correct. Her life away from Nature Coast Clinical Research - Crystal River is all about basketball, baseball, cheerleading, dance and football. 

Before coming to NCCR to work as a Research Assistant, Lisa worked in nursing and rehabilitation. She supports and encourages breastfeeding, babywearing, cloth diapering, and natural/home birthing and her hobbies include sewing, cooking and photography. One of her favorite food indulgences is dark chocolate with almonds, but we suspect that she may have to hide it!!

MyDoc - Research done by doctors from your community!

Our company is made up of local physicians. Doctors from your community, and maybe even your own personal doctor, have helped advance medical knowledge and treatments. Follow the button below to browse a list of the physicians involved in our company. If you decide to sign up, we'll show you a video message from the doctor you select explaining exactly why (s)he loves contributing to clinical research.



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